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Journal of the Korean Wound Management Society 2013;9(2): 91-96. |
| 컬러감자 외피 추출물이 흰쥐 피부화상 치유에 미치는 효과 |
| 한상균1ㆍ임현화2ㆍ이경석1ㆍ유태경1ㆍ이현수2ㆍ홍성빈2ㆍ한만덕1ㆍ김완종1 |
| 1순천향대학교 자연과학대학 생명과학과, 2(주)바이오믹스 |
| Burn Wound Healing of Colored Potato Peel Extract in Rat Skin |
| Sang Kyun Han1, Hyun Hwa Lim2, Gyeong Seok Lee1, Tae Kyeong Yoo1, Hyoun Su Lee2, Seong Bin Hong2, Man Deuk Han1, Wan Jong Kim1 |
| 1Department of Biology, College of Natural Sciences, Soonchunhyang University, Asan, 2Biomix, Goyang, Korea |
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Published online: 30 November 2013. |
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| ABSTRACT |
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A burn is one of the most common and devastating forms of trauma and wound healing is a crucial issue in the treatment of extensive burns. Effects of colored potato extract, which is excellent source of polyphenols including anthocyanins, on the burn (2 degree) wound healing were determined in rats. The wound sizes of experimental groups were rapidly reduced after burn compared to those of control groups. Light microscopically, reepithelialization and recovery of architecture in the injured skin were well accomplished in the experimental groups. Immunohistochemically, positive reaction products of PCNA, which indicates cell proliferation, were more prominent in the injured skin of the experimental groups. Briefly, colored potato extract improved the second-degree burn wound healing in animal model. The results suggest that the extract of colored potato might be expected to be an effective component for development of burn wound healing drug. (J Korean Wound Management Soc 2013;9:91-96) |
| Key Words:
Colored potato extract, Wound healing, Proliferating cell nuclear antigen (PCNA), Rat |
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