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J Korean Wound Management Soc > Volume 9(1); 2013 > Article
Journal of the Korean Wound Management Society 2013;9(1): 46-49.
Polydeoxyribonucleotide (PDRN)을 이용한 만성창상의 치험예
박지훈ㆍ김정윤ㆍ박창식ㆍ허찬영
서울대학교 의과대학 분당서울대학교병원 성형외과학교실
Cases of Polydeoxyribonucleotide (PDRN) Treatment in Pressure Ulcer Patients
Ji Hoon Park, Jung Yoon Kim, Chang Sik Pak, Chan Yeong Heo
Department of Plastic and Reconstructive Surgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea
  Published online: 30 May 2013.
ABSTRACT
The purpose of this study is to report the effects of Polydeoxyribonucleotide (PDRN) in favoring the wound-healing process in chronic pressure sore. 3 adult patients with pressure ulcer were eligible to participate in this study. PDRN were administrated of the same dosage in intramuscular (1 ample, 3 ml, 5.625 mg, 5 days) for 2 weeks and perilesional (1 ample, 3 ml, 5.625 mg, every 3 days) for 4 weeks. After 4 weeks of the treatment period, the PDRN therapy contributed to reducing the patients' wound size and the PUSH score. No adverse events were reported during the treatment. This findings of our study demonstrated that PDRN is able to modify positively the repair processes in pressure soreThis could improve the clinical outcome and decrease the need for additional therapies or hospital stay. (J Korean Wound Management Soc 2013;9:46-49)
Key Words: PDRN, Polydeoxyribonucleotide, Pressure ulcer
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