Development and In Vitro Evaluation of Silver-containing Wound Dressings: II. - Nanosilver-coated Nonwoven Sheets Dressings -

J Korean Wound Management Soc > Volume 2(2); 2006 > Article

Original

Journal of the Korean Wound Management Society 2006;2(2): 83-86.

은 첨가 항균 드레싱의 개발과 항균력 테스트 2 ⁣은 나노섬유 시트⁣

박준규·장학·박종림·김명국·김석화·민경원

서울대학교 의과대학 성형외과학교실, 성형재건연구소

Development and In Vitro Evaluation of Silver-containing Wound Dressings: II. - Nanosilver-coated Nonwoven Sheets Dressings -

Joon Kyu Park, Hak Chang, Jonglim Park, Myung Good Kim, Sukwha Kim, Kyung-won Minn

Department of Plastic & Reconstructive Surgery, Research Institute of Plastic & Reconstructive Surgery, Seoul National University College of Medicine, Seoul, Korea

Published online: 30 November 2006.

ABSTRACT

This study focuses on the design and evaluation of silver-containing wound dressings. A novel wound dressing material was prepared by electrospinning AgNO₃/poly (vinyl alcohol) (PVA) aqueous solution into nonwoven sheets and then treating the sheets by heat. Through SEM and TEM analyses, we observed that the silver nanoparticles exists in the near surface of the electrospun nanofibers. It was presumably thought that the silver nanoparticles were formed by thermo reduction of silver ions from AgNO₃. The AgNO₃/PVA electrospun nanofiber sheets have superior liquid absorbing capacity and excellent antimicrobial ability. Also, the sheets showed quick and continuous release of silver in deionized water for 48 hr due to the high surface area to volume ratio of the electrospun nanofiber webs. (J Korean Wound Care Soc 2006;2:83-86)

Key Words: Silver dressing, Electrospinning, Nanofiber, Antimicrobial property