A Treatment of Diabetic Gangrene Using Negative Pressure Wound Therapy and Regenerative Acellular Dermal Matrix in A Compromised Patient

J Korean Wound Management Soc > Volume 8(1); 2012 > Article

Clinical Report

Journal of the Korean Wound Management Society 2012;8(1): 27-30.

전신상태 불량환자에서 음압요법과 재생성 무세포 진피 기질을 이용한 당뇨족 치험예

최임돈ㆍ정보라ㆍ민경란ㆍ박은수

순천향대학교 의과대학 부천병원 성형외과학교실

A Treatment of Diabetic Gangrene Using Negative Pressure Wound Therapy and Regenerative Acellular Dermal Matrix in A Compromised Patient

Yim Don Choi, Bo Ra Jung, Kyoung Ran Min, Eun Soo Park

Department of Plastic and Reconstructive Surgery, College of Medicine, Soonchunhyang University, Bucheon, Korea

Published online: 30 May 2012.

ABSTRACT

Despite numerous advances, non-healing wounds continue to be a treatment challenge. The negative pressure wound therapy and regenerative acellular dermal matrix have been reported to minimize operative morbidity and speed up the healing time of various chronic wound. So we applied the negative pressure wound therapy (VAC^Ⱂ) and regenerative acellular dermal matrix (Pelnac^Ⱂ) for treatment of the intractable diabetic gangrene with infection, non-healthy granulation tissue, or systemic factor that could impair wound healing. The negative pressure wound therapy facilitated granulation tissue proliferation and eradication of any pre-existing infection. For adequate proliferation of granulation tissue, regenerative acellular dermal matrix is good material, especially preparing skin graft or flap coverage. It provides a favorable microenvironment for bioingrowth by promoting nutritional diffusion and cellular proliferation at the graft site. Diabetic Gangrene were healed by successively with this methods. (J Korean Wound Management Soc 2012;8:27-30)

Key Words: Diabetic foot, Negative pressure wound therapy, Acellular dermal matrix