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Journal of the Korean Wound Management Society 2010;6(2): 077-079. |
| 방사선 치료후 천골부위에 발생한 피하조직의 석회화를 동반한 궤양의 치험예 |
| 김근식1ㆍ정희선1ㆍ이혜경1ㆍ이상엽2 |
| 관동대학교 의과대학 1성형외과학교실, c병리학교실 |
| A Case Report of Radiation Induced Ulcer with Sacral Subcutaneous Calcification Following High-Dose Radiotherapy |
| Keun Sik Kim1, Hii Sun Jeong1, Hye Kyung Lee1, Sang Yeop Yi2 |
| Departments of 1Plastic and Reconstructive Surgery, 2Pathology, Kwandong University College of Medicine, Goyang, Korea |
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Published online: 30 November 2010. |
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| ABSTRACT |
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Radiotherapy is considered as a important therapeutic modalities in cancers. However, the deleterious effects of radiation may have a significant effect on local tissues. The vascular damage and fibrosis are well known late complications of radiation therapy. However, subcutaneous calcification is a very rare complication of radiation therapy. Here we report a case of radiation induced ulcer with sacral subcutaneous calcification. An 87-year-old woman admitted to our department with nonhealing sacral ulcer. She underwent postoperative high dose irradiation for uterine carcinoma thirty years ago. Physical examination revealed the infected ulcer in the sacral area measuring approximately 1.0×1.0 cm. On investigation, her renal function, calcium, phosphate, parathyroid hormone and vitamin D level was normal. A cross-sectional computed tomographic scan of the pelvis showed a amorphous calcification located in the subcutaneous area of left sacral area. Wide excision and biopsy revealed chronic ulcer and calcium deposits in the dermis and subcutaneous tissue. Subcutaneous calcification is a uncommon sequela of fractionated radiotherapy. We report a rare case of sacral subcutaneous calcification after high dose radiation therapy. (J Korean Wound Management Soc 2010;6:77-79) |
| Key Words:
Radiation, Ulcer, Calcification |
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